Ohio For-Profit Healthcare Companies Q4 2025 Financial Performance Overview
Special Quarterly Report - February 10
Trendline Health | OH Pulse | 2026 | Q4’25 Overview

This overview highlights key for-profit players with headquarters, major operations, or significant market presence in Ohio. It focuses on Q4/calendar 2025 (or fiscal equivalent) results, including revenue, earnings/EPS, and year-over-year (YoY) changes where available, along with Ohio-specific notes (e.g., headquarters, facilities, market share, or transitions). Data is from public earnings releases as of early February 2026.
Healthcare Distributors & Supply Chain
Cardinal Health (HQ: Dublin, Ohio)
Leading national distributor of pharmaceuticals and medical products with core Ohio operations.Fiscal Q4 2025 (ended June 30, 2025): Revenue $60.2 billion (flat YoY; +21% adjusted excluding contract expiration). GAAP operating earnings $428 million; GAAP diluted EPS $1.00. Non-GAAP operating earnings +19% to $719 million; non-GAAP diluted EPS +13% to $2.08.
Full fiscal 2025: Revenue $222.6 billion (-2% YoY; +18% adjusted); non-GAAP operating earnings +15% to $2.8 billion; non-GAAP diluted EPS +9% to $8.24. Growth driven by Pharmaceutical and Specialty Solutions segments and acquisitions (e.g., Solaris Health urology MSO).
Physician Enablement & Value-Based Care Platforms
agilon health (HQ: Westerville, Ohio)
Medicare Advantage physician platform with significant Ohio footprint.Q4 2025 and full-year 2025 results pending release (scheduled February 25, 2026). Prior trends indicate continued Ohio-driven expansion in value-based care models.
Hospital & Acute Care Systems (For-Profit Operations in Ohio)
Prime Healthcare (National; facilities in Ohio)
For-profit operator with acute care hospitals in eastern and central Ohio.Key Ohio facilities: Coshocton Regional Medical Center (Coshocton), East Liverpool City Hospital (East Liverpool; recognized for patient safety and top hospital awards in recent years).
National Q4 2025 specifics not isolated in public releases; performance reflects system-wide focus on quality care and community access.
Summa Health (Akron, Ohio; for-profit via HATCo/General Catalyst acquisition in 2025)
Major Northeast Ohio system following 2025 transition to for-profit status. Private entity; no public Q4 2025 financials available.
Post-Acute & Rehabilitation Companies (With Ohio Operations)
Encompass Health (National; multiple inpatient rehabilitation hospitals in Ohio)
Leading for-profit provider of inpatient rehabilitation services.Key Ohio facilities: Encompass Health Rehabilitation Hospital of Toledo (Toledo), The Rehabilitation Institute of Ohio (Dayton; joint venture with Premier Health), Mount Carmel Rehabilitation Hospital (Westerville; affiliate), Encompass Health Rehabilitation Hospital of Cincinnati (Norwood area). Multiple sites recognized on 2025 America’s Best Physical Rehabilitation Centers lists.
National Q4 2025 specifics not isolated; strong national growth in inpatient rehab demand.
Select Medical (National; multiple critical illness recovery and rehabilitation facilities in Ohio)
For-profit specialist in critical illness recovery hospitals (LTACHs) and inpatient rehabilitation.Key Ohio facilities: OhioHealth Rehabilitation Hospital (Columbus and Dublin; joint venture with OhioHealth; ranked among top rehab hospitals nationally in 2025), Select Specialty Hospital – Columbus Victorian Village (Columbus), Select Specialty Hospital – Akron (Akron), Select Specialty Hospital – Cleveland Fairhill (Cleveland), Select Specialty Hospital – Southeast Ohio (Newark). Several locations recognized in U.S. News and Newsweek 2025 rehab rankings.
National Q4 2025 specifics not isolated; ongoing expansions and joint ventures drive performance.
National Behavioral Health Companies (With Ohio Operations)
Universal Health Services (UHS) (National; behavioral facilities in Ohio)
Inpatient and outpatient behavioral health sites (e.g., Windsor Laurelwood in Willoughby, facilities in Youngstown and Maumee). National behavioral segment growth; Ohio contributes to UHS’s ~331-facility behavioral health footprint. Q4 2025 specifics not isolated.Acadia Healthcare (National; multiple Ohio facilities)
Psychiatric and substance use treatment sites (e.g., Columbus, Cincinnati, Cleveland). National expansion focus; Ohio is a key state. Q4 2025 details not publicly detailed.
Payers / For-Profit Health Insurers (Major Operations in Ohio)
UnitedHealthcare (UnitedHealth Group; strong Ohio presence)
Frequently top-ranked in Ohio for premiums, network breadth, and member experience. Broad offerings in commercial, Marketplace, and Medicare Advantage.Parent UnitedHealth Group full-year 2025: Revenues $447.6 billion (+12% YoY); earnings $13.23/share; adjusted earnings $16.35/share. Q4 2025 showed modest net earnings beat; Ohio operations benefit from competitive plan designs.
Aetna (CVS Health; operations in Ohio)
High member satisfaction scores in Ohio commercial plans; strong in employer-sponsored, individual, and Medicare offerings. Parent company health services and insurance segments showed positive growth trends in 2025.Centene (Ambetter from Buckeye Health Plan; major Ohio Marketplace/Medicaid player)
Leads individual/ACA Marketplace enrollment in Ohio.Q4 2025 and full-year 2025 results pending release (scheduled February 6, 2026). National trends and Ohio dual-eligible program selections support continued strong presence.
This overview emphasizes key financial metrics and Ohio-specific ties, incorporating post-acute and rehab providers with notable local footprints. National players’ impact is noted without state-specific financial splits (rarely disclosed publicly). For post-release updates (e.g., agilon health, Centene), refer to company investor relations pages.
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